Operational Excellence: The Engine of Enterprise-Wide Transformation in Manufacturing Manufacturing excellence is increasingly being recognized not just as a goal but as a capability—one that is achieved through disciplined and sustained focus on operational excellence . Operational Excellence (OpEx) is often misconstrued as a collection of tools or a cost-cutting initiative. In reality, it is a comprehensive strategic discipline that enables transformation across the entire manufacturing value chain—from sourcing to final delivery. For manufacturers, OpEx is about harmonizing speed, cost, quality, and innovation, while fostering cross-functional alignment and enterprise agility. This article explores a modern operational excellence framework tailored for manufacturers, supported by real-world examples from India, Europe, and the United States. It also showcases how organizations can leverage their Center for Manufacturing Excellence to institutiona...